THEME 1

create a culture of donation

Laurie
Blackstock

Patient Co-Lead

theme 2

Inform universal practices for donation

James

Shapiro

Co-Lead

Nathalie

Trudeau

Patient Co-Lead

theme 3

Engineer and allocate better grafts

Markus

Selzner

Co-Lead

Shilpa

Raju

Patient Co-Lead

THEME 4

Tailor an optimal immune system for each patient

Atul

Humar

Co-Lead

Elaine

Yong

Patient Co-Lead

theme 5

restore long-term health

Sunita

Mathur

Co-Lead

Sandra

Holdsworth

Patient Co-Lead

research

Platforms

Mélanie

Dieudé

Principal Scientific Office

and Research Services and Data Innovation Platform Lead

Marie-Chantal

Fortin

Patient Researcher Partnership Platform Lead

Sylvain

Bédard

Patient Researcher Partnership Platform Lead

Lee Anne

Tibbles

HQP Training Lead

Biographies

Matthew Weiss - Theme 1 Lead - Dr. Matthew Weiss is a pediatric intensivist working in Quebec City at the Centre Hospitalier Universitaire de Québec since 2010 and an assistant clinical professor of pediatrics at the Université Laval. He is involved in multiple provincial and national donation roles, including medical director of donation at Transplant Québec, co-founder of the guideline development group (GUIDDE) at Canadian Blood Services, and a co-lead of the Core-3 (educational platform) of the Canadian National Transplant Research Program. He led the development of the national guidelines on pediatric donation after circulatory donation of death (pDCD) and hopes to follow that work with a continued push to document improvements in pDCD practices in Canada and internationally.

 

Jennifer Chandler - Theme 1 Co-Lead - Ms. Jennifer A. Chandler studies the legal and ethical aspects of biomedical science and technology, focusing on organ donation and transplantation, end of life care, mental health law and policy, and neuroethics. She holds the Bertram Loeb Research Chair – a research chair focused on organ donation and transplantation from the perspective of the humanities and social sciences. 

She sits on multiple ethics advisory boards for organ donation and transplantation including Trillium Gift of Life Network and the Canadian Society of Transplantation. In addition, she serves on the Board of Directors of the Canadian Institute for the Administration of Justice, as well as the CCA Expert Panel on Medical Assistance in Dying. In 2016, she was elected to the Board of Directors of the International Neuroethics Society, where she leads the Emerging Issues Task Force, and serves on international editorial boards in the field, including Clinical Neuroethics, Advances in Neuroethics (Springer), and Law, Neuroscience and Human Behavior (Palgrave-MacMillan).

 

Maureen Meade - Theme 2 Lead - Dr. Maureen Meade is a critical care consultant and hospital donation physician at Hamilton Health Sciences, where she also serves as Director of Research for the multidisciplinary intensive care units. At McMaster University, she is a professor in the Department of Medicine and Cochair of the CLARITY Research Methods Centre. Dr. Meade is Director of the Canada-DONATE Research Program, she co-leads innovative outcomes projects for the Canadian National Transplant Research Program, and she is a coinvestigator in the DePPaRT study.

 

James Shapiro - Theme 2 Co-Lead - Dr. James Shapiro studied Medicine in Newcastle and trained in Surgery in Bristol. He developed a longstanding interest in islet transplantation as a medical student. He has been on Faculty at the University of Alberta since 1998, where he now holds the Canada Research Chair in Transplantation Surgery and Regenerative Medicine. He directs the living donor liver transplant and the islet transplant programs in Edmonton. He was the lead investigator on the famous “Edmonton Protocol” cell transplant treatment for diabetes. 

Dr. Shapiro is the recipient of several prestigious awards, including the Hunterian Medal from the Royal College of Surgeons of England, the Paul E. Lacy Gold Medal, the Gold Medal in Surgery from the Royal College of Physicians and Surgeons of Canada, the Governor General's Gold Medal, the Queen’s Jubilee Medal, the Meritorious Service Medal, and was inducted as a Fellow of the Royal Society of Canada.

 

Jean-Sébastien Delisle - Theme 3 Lead and Associate Director of HCT - Dr. Jean-Sébastien Delisle is a clinician-scientist in hematopoietic cell transplantation, T-cell biology and T-cell immunotherapies. Dr. Delisle established his research group in 2010 and rapidly develop a basic and translational research program in the area of cellular immunotherapies. A believer in the rapid translation of science from the bench to the bedside, Dr. Delisle led the development and implementation of T-cell culture process that are used to treat transplantation patients. These therapies are the first of their type in the world.

 

Markus Selzner - Theme 3 Co-Lead - Dr. Markus Selzner is an Assistant Professor at the Department of Surgery at the University of Toronto. He obtained his education in medicine and training in General Surgery in Germany. He conducted post-graduate research at Duke University and Zurich University under the mentorship of Professor Pierre-Alain Clavien. Dr. Selzner completed a Fellowship in Abdominal Organ Transplantation at the University of Toronto in 2007 and has worked as a Clinical Associate in Transplantation at UHN since 2016.

 

Megan Levings - Theme 4 Lead - Dr. Megan Levings is an internationally-renowned immunologist studying immune balance in humans. She has been working in the area of human immunology for 20 years, and was the first to show that human regulatory T cells could be isolated from blood then expanded and used as a cell therapy to regulate immune responses in the context of transplantation. She has significant experience leading teams within large networks, such as the CNTRP and the Genome Canada iGenoMed consortium. Her commitment to enabling large-scale research opportunities is evidenced by leadership of the FOCIS Centres of Excellence, current and past membership on the CIHR Chronic Disease and Infection and Immunity Advisory Boards, respectively, and participation in The Transplantation Society virtual global laboratory initiative. She also brings a track record of working with industry and international research teams, including collaborations with Beckman Coulter to develop new standardized flow cytometry assays, the Immune Tolerance Network for immune monitoring in the clinical trial of ustekinumab (aIL-12/23 p40) for type 1 diabetes, and membership on the JDRF Biomarkers working group.

 

Atul Humar - Theme 4 Co-Lead - Dr. Atul Humar is a Professor in the Department of Medicine, University of Toronto. Dr. Humar received his medical degree from the University of Ottawa. He completed his residency and did further training in Transplant Infectious Diseases in Toronto and Boston. Dr. Humar’s research interests are in virology with a focus on the pathogenesis of herpesvirus infections, post-transplant. He is involved in basic and clinical research assessing immunologic and virologic determinants of infection. Dr. Humar is the Director of Multi Organ Transplant Program at the University Health Network and the University of Toronto Transplant Institute. He is the Past-President of the Canadian Society of Transplantation (CST). He was elected to President of the CST in October 2015. He is the Project Lead of Canadian National Transplant Research Program (CNTRP) P5 Core; Predicting and controlling viral complications of transplantation.

 

Tom Blydt-Hansen - Theme 5 Lead - Dr. Tom Blydt Hansen is Director of the Pediatric Multi-organ Transplant Program at BC Children’s Hospital and past president of the Canadian Society of Transplantation. His research program is on biomarkers for kidney injury in transplantation. His work extends to numerous collaborations and he is co-investigator on several nationally funded transplant research studies including VIRTUUS, TAKE-IT TOO, CKiD, iCARE, CAN-RESTORE and CNTRP. His leadership roles include Board membership of NAPRTCS and Chair of the Outreach Program for the International Pediatric Transplant Association. Dr. Blydt-Hansen also leads CNTRP New Initiative committee, bringing new investigators to the program and promoting connections between research teams.

 

Sunita Mathur - Theme 5 Co-Lead - Dr. Sunita Mathur is a physical therapist and Assistant Professor in the Dept of Physical Therapy, University of Toronto. She is the co-founder and co-Chair of CAN-RESTORE (Canadian Network for Rehabilitation and Exercise for Solid Organ Transplant Optimal Recovery), which aims to improve healthy active living in solid organ transplant patients, through translational research, dissemination of evidence and partnerships. Dr. Mathur directs the Muscle Function & Performance Research Lab, which focuses on evaluation sarcopenia and frailty in people with advanced lung disease and lung transplantation; and exercise-training pre- and post-transplant.

 

Mélanie Dieudé - Principal Scientific Officer and Research Services and Data Innovation Platform Lead - Dr. Mélanie Dieudé is an immunologist, researcher at CRCHUM and the Scientific Integration manager of the Canadian National Transplantation Research Program (CNTRP). She obtained her PhD at Université de Montréal in 2004, followed by fellowships at McGill University (2005-2009) and Université de Montréal (2009-2011). Recipient of numerous distinctions such as the Scientific Personality of the Year - LaPresse (2017) and American Transplant Congress Young Investigator award (2011), her research aims at determining the impact of tissue injury on autoimmune responses of importance in graft versus host disease and solid organ rejection. Dr. Dieudé has been implicated in the development and the scientific integration of the Canadian National Transplantation Research Program (CNTRP) since 2014.

 

Marie-Chantal Fortin - Patient Researcher Partnership Platform Lead - Dr. Marie-Chantal Fortin is a transplant nephrologist at the Centre hospitalier de l’Université de Montréal (CHUM), a researcher at the Research Centre of the CHUM and an associate professor at the Faculty of Medicine of the Université de Montréal. She received her medical degree from the Université de Sherbrooke. She completed her nephrology residency at the Université de Montréal. She has completed a PhD in bioethics in 2008 at the Université de Montréal. She is also a researcher in the Canadian National Transplant Research Program (CNTRP) and the co-leader of the Core 4 (the patient-researcher partnership platform). Her research interests are related to transplantation ethics and patient and researcher partnership in research and clinical care. She chairs the ethics committee of the Canadian Society of Transplantation and is a member of the ethics committee of Transplant Québec, the Royal College of Physicians and Surgeons of Canada, the Canadian Blood Services and the Collège des médecins du Québec. She is also a research scholar of the FRQS.

 

Sylvain Bédard - Patient Researcher Partnership Platform Lead - Sylvain Bédard lived 20 years with hypertrophic cardiomyopathy before becoming a heart transplant recipient in 2000. Professionally, Mr. Bédard was technical director for musicals, tv shows and international events and a teacher at the National Theatre School of Canada. After receiving the gift of life, he climbed Mont-Blanc (4800m) in 2003 and became the first heart transplant recipient in history to climb over 6000m in Bolivia, Sajama Mountain at 6500m. Gold medalist at the World Transplant Games, he also went on an expedition in the Sahara desert. Motivational speaker: Mr. Bédard has published his journey in the Journal of Heart and Lung Transplantationand has been an invited speaker for the Canadian Cardiovascular Society (CSS), the Canadian Society of Cardiac Surgeons, the Canadian Association of Cardiac Rehabilitation, at the Toronto Heart Summit and many others. His expedition to Bolivia was covered by Radio Canada, the Discovery channel,and Canadian news outlets such as La Presse, the Medical Post, Macleans, the Globe and Mailand Reader's Digest. Mr. Bédard became CNTRP Patient Co-Lead in 2016.

 
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