New gene therapy and ex vivo heart studies set to begin in Edmonton
CNTRP researchers in Edmonton received a $1-million award this week — the largest single research award in the University Hospital Foundation’s history — for a project that could change the field of heart transplantation.
The project, led by principal investigator Dr. Jason Dyck, involves using gene therapy to genetically modify a transplantable heart to make it more resistant to rejection and less likely to fail. By delivering therapeutic genes to the heart, the goal is that it will improve outcomes for transplant patients.
Dr. Jason Dyck, the director of the Cardiovascular Research Centre at the University of Alberta, is working on the project alongside CNTRP Researchers Dr. Lori West, the interim director and research director of the Alberta Transplant Institute, and Dr. Darren Freed and Dr. Jayan Nagendran, surgeons and researchers at the Mazankowski Alberta Heart Institute.